里見 元義¹, 宮川 幸子¹, 森島 正恵², 山田 芳弘³, 小国 弘量⁴, 中村 憲司¹, 高尾 篤良¹

Gengi SATOMI¹, Sachiko MIYAGAWA¹, Masae MORISHIMA², Yoshihiro YAMADA³, Hirokazu OGUNI⁴, Kenji NAKAMURA¹, Atsuyoshi TAKAO¹

¹東京女子医科大学日本心臓血圧研究所循環器小児科, ²東京女子医科大学日本心臓血圧研究所研究部, ³(現)国立長崎中央病院, ⁴(現)東京女子医大小児科

¹Department of Pediatric Cardiology Heart Institute of Japan,Tokyo Women's Medical College, ²Department of Experimental Laboratory, Heart Institute of Japan,Tokyo Women's Medical College, ³Department of Pediatrics, Nagasaki Chuou Hospital, ⁴Department of Pediatrics,Tokyo Women's Medical College

キーワード : left heart, contrast echocardiography, Perfluorochemicals, Intralipos

　In order to determine a possible transvenous left heart contrast agent, we performed contrast two-dimensional echocardiography in 18 dogs using three kinds of perfluochemicals (Fluosol-DA, FC-43 and Perfluoroctyl bromide) and Intralipos. The 5 ml of Fluosol-DA 20% and 5 ml of Intralipos yielded best contrast in the left heart in all of the dogs. Oxygenation of the Fluosol-DA 20% was not helpful for increasing the success rate of left heart contrast.
　The dissolution and dilution of small contrast particles reaching the left sided chambers through the capillary bed of the lung was speculated as a source of the contrast echoes in the left heart.