森安 史典¹, 西田 修¹, 伴 信之¹, 中村 武史¹, 越智 次郎¹, 酒井 正彦¹, 内野 治人¹, 塚田 英昭², 三宅 健夫², 宋 泰成³

Fuminori MORIYASU¹, Osamu NISHIDA¹, Nobuyuki BAN¹, Takefumi NAKAMURA¹, Jiro OCHI¹, Masahiko SAKAI¹, Haruto UCHINO¹, Hideaki TSUKADA², Takeo MIYAKE², Yasunari SOH³

¹京都大学医学部第一内科, ²京都大学医学部老年科, ³県立尼崎病院内科

¹The First Department of Internal Medicine, Kyoto University, ²The Department of Geriatrics, Kyoto University, ³The Department of Internal Medicine, Amagasaki Prefectual Hospital

キーワード : Ultrasonic duplex system, Portal vascular resistance, Portal blood flow, Portal venous pressure

　The portal vascular resistance was measured percutaneously in 28 patients with chronic liver diseases. The portal vascular resistance (PVR) was calculated from the portal blood flow (PBF), the portal venous pressure (PVP), and the hepatic venous pressure (HVP), all of which were measured simultaneously. The PVR was calculated by the equation, PVR=(PVP-HVP)/PBF. The PBF was measured by an ultrasonic duplex system composed of a real-time B-mode scanner and a pulsed Doppler flowmeter. The PBF was calculated from the cross-sectional area measured by the B-mode and the average blood flow velocity measured by the Doppler mode. The PVP was measured by percutaneous transhepatic catheterization under ultrasonic guidance and the HVP was measured by venous catheterization. The results are as follows; The PVP was 17.6±3.9 mmHg (mean±S.D.) in patients with chronic active hepatitis (CAH, n=10) and 20.3±2.4 mmHg in cirrhosis (LC, n=18). The PBF was 973±395 ml/min in CAH and 778±272 ml/min in LC. The PVR was 0.68±0.33 mmHg・ml^-1・min・kgBW in CAH and 1.25±0.73 mmHg・ml^-1・min・kgBW in LC. In the PVR, there was a significant difference between CAH and LC.