高木 等¹, 熊田 卓², 中野 哲², 金森 勇雄¹, 木村 得次¹, 吉田 宏¹

Hitoshi TAKAGI¹, Takashi KUMADA², Satoshi NAKANO², Isao KANAMORI¹, Tokuji KIMURA¹, Hiroshi YOSHIDA¹

¹大垣市民病院放射線技術部, ²大垣市民病院消化器科

¹The Department of Radiology. Ogaki Municipal Hospital, ²The Department of Gastroenterology, Ogaki Municipal Hospital

キーワード : Doppler, Nitroglycerin, Portal hypertension

To investigate the effects of Nitroglycerin on Portal Hypertension, we measured the portal hemodynamics of ten patients with chronic liver diseases (7 with liver cirrhosis and 3 with idiopathic portal hypertension) using the Ultrasonic Doppler Duplex System.
Mean blood flow velocity and volume in the portal and splenic veins decreased significantly after infusion of Nitroglycerin (p We concluded that Nitroglycerin reduced portal blood flow without a significant reduction in arterial blood pressure. The optimal blood concentration of Nitroglycerin to get above effect was 0.5∼0.8γ.