室月 淳, 岡村 州博, 上原 茂樹, 遠藤 英敬, 岩本 充, 矢嶋 聴

Jun MUROTSUKI, Kunihiro OKAMURA, Shigeki UEHARA, Hidetaka ENDO, Mitsuru IWAMOTO, Akira YAJIMA

東北大学医学部産婦人科

Department of Obstetrics and Gynecology, Tohoku University School of Medicine

キーワード : Trisomy 18, Crown-rump length, Biparietal diameter, Femur length , Ultrasonographic screening

A retrospective analysis of the ultrasonic growth patterns of 16 cases of trisomy 18 is presented. The patterns were examined by the crown-rump length in the first trimester and by the biparietal diameter and femur length in the second trimester or later. The crow-rump length of trisomy 18 fetuses was smaller than normal. Significant growth delay detected during the first trimester may be a useful marker for trisomy 18. The biparietal and femur growth expressed the low profile type in trisomy 18. The growth of biparietal diameter and femur length was below the 5th percentile from early in the second trimester, but usually without cessation. The femur length was more retarded than the biparietal diameter. The biparietal diameter/femur length ratio may prove superior to trisomy 18 screening methods.