野村 康晴¹, 松田 康雄², 藪内 以和夫¹, 位藤 俊一²

Yasuharu NOMURA¹, Yasuo MATSUDA², Iwao YABUUCHI¹, Toshikazu ITOH²

¹大手前病院内科, ²大手前病院外科

¹Department of Internal Medicine, Otemae Hospital, ²Department of Surgery, Otemae Hospital

キーワード : Contrast agent, Hepatocellular carcinoma, Quantitative analysis, Ultrasound

We attempted the quantitative analysis of vascularity in hepatocellular carcinoma (HCC) nodules using enhanced ultrasonography (enhanced US). Our first goal was to determine the most appropriate parameter for this purpose. Enhanced US was performed on 58 HCC nodules smaller than 3 cm in diameter. On 17 of the 58 nodules, nine parameters were calculated using the time intensity curve (TIC) obtained from two regions of interest (ROIs): one placed on the tumor itself, the other on the non-tumor hepatic parenchyma. As was the case with enhanced US, these values were compared with those obtained from the time density curve (TDC) derived from digital subtraction angiography (DSA) and may be regarded as demonstrating actual arterial vascularity. Of these parameters, only vascularity index (V.I.), which represents maximum slope ratio of tumor to parenchyma, produced a significant correlation between TIC and TDC (r=0.552, p