妹尾 大作¹, 秦 利之¹, 青木 昭和¹, 秦 幸吉¹, 木村 正彦², 山口 清次²

Daisaku SENOH¹, Toshiyuki HATA¹, Showa AOKI¹, Kohkichi HATA¹, Masahiko KIMURA², Seiji YAMAGUCHI²

¹島根医科大学産科婦人科, ²島根医科大学小児科

¹Department of Obstetrics and Gynecology, Shimane Medical University, ²Department of Pediatrics, Shimane Medical University

キーワード : Antenatal diagnosis, Liver calcification, Ultrasound

A pregnant 26-year-old woman (gravida Ⅳ, para Ⅲ) came to the ultrasonography clinic for routine screening at 21 weeks of gestation. Fetal solitary liver calcification measuring 6×5×4 mm was identified at the left side of the umbilical vein in the left hepatic lobe. Fetal growth was normal, and there were no other anomalies. The hyperechoic nodule grew gradually until the 28th week, when it measured 8×7×5 mm, but no changes were found thereafter. At 39 weeks and 3 days, the patient was vaginally delivered of a viable male infant weighing 3004 g. Ultrasonography showed granular hyperechoic lesions in the S₂ area of the left hepatic lobe, and psychomotor developmental delay was found when the infant was 3 months old. Intracranial calcification was not detected, however. The connection between fetal liver calcification and postnatal psychomotor developmental delay remains obscure.