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英文誌(2004-)

Journal of Medical Ultrasonics

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1998 - Vol.25

Vol.25 No.05

Original Article(原著)

(0613 - 0618)

造影エコー法におけるDigital Subtractionの検討

Study of Contrast-Enhanced Ultrasonography Using Digital Subtraction Angiography System

野田 孝浩1, 2, 熊田 卓1, 2, 日比 敏男1, 伊藤 益弘1, 竹島 賢治1, 2, 杉田 文芳1, 2, 矢橋 俊丈1, 2, 佐々 敏1, 木村 得次1, 中野 哲2

Takahiro NODA1, 2, Takashi KUMADA1, 2, Toshio HIBI1, Masuhiro ITOH1, Kenji TAKESHIMA1, 2, Fumiyoshi SUGITA1, 2, Toshitake YABASHI1, 2, Toshi SASSA1, Tokuji KIMURA1, Satoshi NAKANO2

1大垣市民病院超音波検査室, 2大垣市民病院消化器科

1Division of Abdominal Ultrasound, Ogaki Municipal Hospital, 2Department of Gastroenterology, Ogaki Municipal Hospital

キーワード : CO<SUB>2</SUB> microbubbles, Enhanced ultrasonography, Subtraction, Hepatocellular carcinoma, Quantitative analysis

In contrast-enhancement ultrasonography (CEUS) with arterial injection of carbon dioxide microbubbles, it is difficult to evaluate degree of enhancement of hyperechoic or hypoechoic nodules using the criterion used in plain US, because degree of enhancement of each nodule compared with that of the surrounding liver parenchyma is judged visually in CEUS. We devised a new method for estimating vascularity of nodules in the liver from CEUS (USDSA) images. Here we evaluated the hemodynamic patterns of 51 nodules obtained using USDSA and compared the vascular patterns of 10 nodules that appeared hyperechoic in plain US images with results obtained with quantitative analysis. USDSA proved useful in estimating the vascularity of hyperechoic lesions in plain US, but was not necessary when estimating vascularity of hypoechoic lesions in plain US images. Although all 10 hyperechoic nodules were diagnosed as isovascular nodules by CEUS, 8 were diagnosed as hypovascular nodules and 2 as vascular spot in hypovascular nodules by USDSA. Vascularity index of the 10 nodules ranged from 0.00 to 0.88 and was less than 1.00 in all cases. Vascularity index of the vascular spot indicated by USDSA was higher than that of other nodular lesions. These findings demonstrate the hemodynamic heterogeneity of tumors.