真鍋 后輝¹, 舛形 尚¹, 水重 克文¹, 陸 新¹, 木下 晶¹, 植田 孝¹, 野崎 士郎¹, 阪本 整司¹, 千田 彰一², 松尾 裕英¹

Kimiteru MANABE¹, Hisashi MASUGATA¹, Katsufumi MIZUSHIGE¹, Xin LU¹, Aki KINOSHITA¹, Takashi UEDA¹, Shiro NOZAKI¹, Seiji SAKAMOTO¹, Shoichi SENDA², Hirohide MATSUO¹

¹香川医科大学第2内科, ²香川医科大学総合診療部

¹Second Department of Internal Medicine Kagawa Medical University, 1750-1 Miki-cho, Kita-gun, Kagawa 761-0793, Japan, ²Department of Primary Care Medicine Kagawa Medical University, 1750-1 Miki-cho, Kita-gun, Kagawa 761-0793, Japan

キーワード : Cyclic alteration , Mitral regurgitation , Thick mitral valve

Although alteration in mitral valve (MV) thickness has been observed during the cardiac cycle in patients with mitral valve prolapse (MVP), data regarding cyclic alteration in MV thickness in the age-related thickened MV are limited. We measured MV thickness variation in age-related thickened MV under diastole (D) and systole (S) at their thickest points on the echocardiogram and calculated percent of change in thickness from systole to diastole (%ΔW) using the following equation: %ΔW=(D-S)X100/D. The subjects were 35 patients with age-related thickened MV (D≥4 mm, aged 72±13 years), 8 with mitral valve prolapse (aged 41±18 years), 10 with rheumatic mitral stenosis (MS) (aged 66±9 years), and 25 control subjects (D≤3.9 mm, aged 50±16 years). The %ΔW in age-related thickened MV was greater than that in controls (59±8% vs 35±7%, p2 vs 17±44 mm², p