王 怡¹, 伊東 紘一¹, 谷口 信行¹, 藤栄 寿雄², 川井 夫規子¹, 中村 みちる¹, 尾本 きよか¹, 横田 京子¹, 小野 倫子¹

Yi WANG¹, Kouichi lTOH¹, Nobuyuki TANIGUCHI¹, Hisao TOEI², Fukiko KAWAI¹, Michiru NAKAMURA¹, Kiyoka OMOTO¹, Kyoko YOKOTA¹, Tomoko ONO¹

¹自治医科大学臨床病理学, ²自治医科大学放射線医学教室

¹Department of Clinical Pathology, Jichi Medical School (3311-1 Yakushiji, Minamikawachi-machi, Kawachi-gun, Tochigi 329-0498, Japan), ²Department of Radiology, Jichi Medical School (3311-1 Yakushiji, Minamikawachi-machi, Kawachi-gun, Tochigi 329-0498, Japan)

キーワード : Computed tomography, Idiopathic interstitial pneumonia, Liver diseases, Texture analysis, Ultrasonography

We used texture analysis with the co-occurrence matrix method to analyze ultrasonograms from normal and diseased livers , and X-ray CT images obtained from normal cases and cases of idiopathic interstitial pneumonia. Ten cases of normal, fatty, and cirrhotic livers; 10 cases of normal lungs; and 10 cases of idiopathic interstitial pneumonia, all confirmed by clinical findings, laboratory data, surgery, or biopsy, were included in this study. We compared the results of texture analysis in normal and diseased livers under the same conditions of gain, focus, magnification rate, probe frequency, and depth of the region of interest. Here we discuss the relationship between Fisher ratio of texture analysis and pathological character. Although the normal and diseased liver groups did not differ significantly, the different pathological grades of fibrosis and the different size of nodules in the cirrhotic and normal liver groups did have different Fisher ratios. We compared the results of texture analysis with images obtained from normal cases and cases of idiopathic interstitial pneumonia. Significant differences between normal lungs and those with idiopathic interstitial pneumonia were also found. We thus think that texture analysis can be used to analyze ultrasonograms obtained from lesions of different pathological grades and to classify CT images as well.