日比 敏男¹, 熊田 卓², 竹島 賢治¹, 伊藤 益弘¹, 野田 孝浩¹, 後藤 繁優¹, 杉田 文芳¹, 佐々 敏¹, 市川 秀男¹, 中野 哲²

Toshio HIBI¹, Takashi KUMADA², Kenji TAKESHIMA¹, Masuhiro ITO¹, Takahiro NODA¹, Shigemasa GOTO¹, Fumiyoshi SUGITA¹, Toshi SASSA¹, Hideo ICHIKAWA¹, Satoshi NAKANO²

¹大垣市民病院形態診断室, ²大垣市民病院消化器科

¹Department of Morphologic Diagnosis, Ogaki Municipal Hospital, 4-86 Minaminokawa-cho, Ogaki-shi Gifu 503-8502, Japan, ²Department of Gastroenterology, Ogaki Municipal Hospital, 4-86 Minaminokawa-cho, Ogaki-shi Gifu 503-8502, Japan

キーワード : Doppler ultrasonography, Dynamic magnetic resonance Imaging , Hepatocellular carcinoma, Transcatheter arterial embolization

This study was undertaken to determine the value of Doppler ultrasonography in the early evaluation of therapeutic efficacy of hepatocellular carcinoma after transcatheter arterial embolization (TAE). Fifty-two nodules in which tumor vascularity had been detected by Doppler ultrasonography before TAE were examined in 41 patients. Doppler signals were evaluated 1 week after TAE, and the results were compared with tumor vascularity as determined by dynamic magnetic resonance imaging (dynamic MRI), which was used as the gold standard. The sonographic signal disappeared in 41 (79%) of the 52 nodules and remained in 11 (21%). All nodules in which intratumor vascularity had been detected showed positive stain on dynamic MRI. Four of 41 nodules in which the sonographic signal disappeard showed positive stain on dynamic MRI. The Sensitivity of Doppler ultrasonography was 73%; specificity, 100%; and accuracy, 92%. Flow signal in deeply (≥5 cm) located small (≤3 cm) nodules tended to be more difficult to detect. We conclude that Doppler ultrasonography warrants use after TAE in the early evaluation as a specific and noninvasive imaging technique.