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英文誌(2004-)

Journal of Medical Ultrasonics

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2001 - Vol.28

Vol.28 No.05

Case Report(症例報告)

(J779 - J784)

Levovist静注による造影カラードプラ法が腫瘍血流信号描出に有用であった胸膜下肺癌の2例

The Usefulness of Color Doppler Sonography Using Intravenous Contrast Agent Levovist in Two Cases of Subpleural Lung Cancer

浜崎 直樹1, 江川 信一1, 竹下 修治1, 仲川 房幸2, 空 昭洋3, 吉田 和弘3, 鴻池 義純4, 今井 幸子5, 平井 都始子6, 成田 亘啓7

Naoki HAMAZAKI1, Shinichi EGAWA1, Shuuji TAKESHITA1, Fusayuki NAKAGAWA2, Akihiro SORA3, Kazuhiro YOSHIDA3, Yoshizumi KOUNOIKE4, Yukiko IMAI5, Toshiko HIRAI6, Nobuhiro NARITA7

1済生会奈良病院内科, 2済生会奈良病院放射線科, 3済生会奈良病院臨床検査部, 4平成記念病院内科, 5奈良県立三室病院放射線科, 6奈良県立医科大学腫瘍放射線科, 7奈良県立医科大学第2内科

1Department of Internal Medicine, Saiseikai Nara Hospital, 2Department of Radiology, Saiseikai Nara Hospital, 3Department of Clinical Laboratory, Saiseikai Nara Hospital, 4Department of Internal Medicine, Heisei Memorial Hospital, 5Department of Radiology, Nara Prefectural Mimuro Hospital, 6Department of Oncoradiology, Nara Medical University, 7Second Department of Internal Medicine, Nara Medical University

キーワード : color Doppler ultrasonography, intravenous contrast agent, levovist, power mode, lung cancer

We recently encountered two cases that suggested that Levovist, an intravenous contrast agent, was useful for its ability to enhance color signals in the color Doppler ultrasonographic imaging in subpleural lung cancer, especially in lung cancer with relatively poor flow and tortuous color flow in part of the lesion. Case 1 was that of a 66-year-old woman in whom a tumor shadow was detected in S1+2 of the left lung. The diagnosis of squamous cell carcinoma of the lung was based on the results of broncoscopic examination. The B-mode ultrasonogram showed a hypoechoic tumor with pleural invasion. Power Doppler US color flow patterns indicated tortuous color flow in part of the lesion. Power Doppler ultrasonograms acquired after injection of Levovist showed enhanced color flow signals inside and around the periphery of the tumor. Color flow signals increased from the partial to the whole type. Case 2 was that of a 69 year-old man with a mass shadow in S1+2 of the left lung. The diagnosis of squamous cell carcinoma of the lung was based on results of broncoscopic examination. The B-mode ultrasonogram showed a hypoechoic tumor with pleural invasion. The power Doppler US color flow pattern indicated tortuous color flow in part of the lesion. Power Doppler ultrasonograms acquired after injection of Levovist showed enhanced color flow inside and around the periphery of the tumor. Color flow pattern did not change after injection of Levovist . These two cases suggest that Levovist is useful in detecting the vessels of subpleural lung cancer.