山本 徳則, 後藤 百万

Tokunori YAMAMOTO, Momokazu GOTOH

名古屋大学医学系研究科泌尿器科

Department of Urology, Nagoya University Graduate School of Medicine

キーワード : microcirculation, contrast-enhanced ultrasound, kidney, prostate, urology

腎・泌尿器科領域の各臓器血流測定を造影超音波検査を用いて微小循環の観点から述べる．超音波造影剤（Sonazoid^®）は安定した剤型なので，長期間の腎・泌尿器科領域の各臓器の血流測定を可能にした．具体的に，腎機能評価，腫瘍質的診断そして前立腺肥大症の血流評価，前立腺癌の質的診断と広く応用されている．新しい腎機能評価，腎細胞癌の診断率向上そして新しい前立腺肥大症の評価，前立腺癌の診断率の向上に寄与することが期待される．

Since the second-generation ultrasound contrast agent Sonazoid^® has a stable shell, it enables visualization of the urologic vasculature for a long period of time. We therefore evaluated changes in contrast-enhanced ultrasound (CEUS) imaging of urological organs. It is used for the diagnosis of renal function by enhancing small normal blood vessels. Also, pathological changes in blood vessels are diagnosed by enhancing abnormal vessels. Furthermore, it is applied to spread of renal function and prostatic function and is used for graft function and pharmacological evaluation, respectively. The blood-flow distribution and tumor itself in the case of renal and prostatic tumors are also enhanced. It is expected that effective use of the ultrasound contrast agent will increase the diagnostic rate of renal cell carcinoma and the positive rate of prostate biopsy and lessen the number of biopsy sites.