今井 康博¹, 水谷 恵次¹, 高橋 昭夫¹, 加藤 忠之¹, 奥村 健二¹, 高井 正昭²

Yasuhiro IMAI¹, Keiji MIZUTANI¹, Akio TAKAHASHI¹, Tadayuki KATO¹, Kenji OKUMURA¹, Masaaki TAKAI²

¹国家公務員共済組合立名城病院循環器科, ²国家公務員共済組合立名城病院生理部

¹Division of Cardiology, Meijo Hospital, ²Division of physiology, Meijo Hospital

キーワード : carbondioxide microbubbles, shaking the syringe, safety of contrast echocardiography

A new method of contrast echocardiography by using a solution containing microbubbles of carbondioxide was developed and clinical safety of this method was investigated by means of ammal (rabbit) experiments.
The solution used was made by following technique : About 5 ㎖ of carbondioxide was introduced into the syringe filled with about 15 ㎖ of 20% glucose. Then the syringe was shaken strongly for mixing and making microbubbles of carbondioxide in the solution. In clinical use, about 10 ml of the solution thus obtained was injected into the peripheral vein just after shaking.
By this method, very clear contrast echoes were observed in almost all cases and no side effects were revealed.